Does HGH increase penis size?
Hormones such as the human growth hormone (HGH) and testosterone are some of the main factors that regulate the growth and development of the penis since the intrauterine development of the male embryo.
The deficiency of either of those hormones can lead to micropenis in boys.
HGH therapy can successfully increase penis size in children with GHD who are suffering from micropenis.
In fact, congenital GHD is the most common cause of micropenis, although the condition itself is a rare disorder that affects about 0.01–0.02% of newborn males.
It is defined as stretched penile length in newborns under 0.7 inches (2 cm) and often includes underdeveloped testes. Studies report that if the micropenis is not properly treated with HGH, it will most likely persist throughout adulthood.
On the other hand, starting growth hormone treatment during childhood can help most patients eventually reach a normal penis size.
According to one study, long-term HGH therapy helped 7 out of 8 children with micropenis successfully achieve normal penis size by adulthood. The children also achieved normal body height and development.
HGH promotes penile and testicular growth by stimulating the synthesis of IGF-1 in their tissues. IGF-1 is a major growth factor that controls the growth and development of most organs in the human body.
Similar studies in adults are rare. Currently, there is only one case study that reports a significant increase in penis size in an adult with congenital GHD and micropenis who was treated simultaneously with HGH and testosterone therapy.
HGH and IGF-1 may also play a role in male sexual function. Some studies have found a correlation between IGF-1 levels and Sexual Health Inventory for Men (SHIM) scores. Higher IGF-1 levels were associated with better sexual health.
SHIM is a questionnaire used for the evaluation of erectile dysfunction (ED).
Some laboratory experiments also suggest that growth hormone may stimulate the relaxation of the vessels in the penis, which correlates with better blood flow and improved erectile function.
Sources: NCBI, besthghdoctor